Attempted0/10
Remaining10
Correct Incorrect Unanswered
1
2
3
4
5
6
7
8
9
10

A 46-year-old woman presents with progressive weight gain, fatigue, proximal muscle weakness, and easy bruising over 6 months. She has developed facial rounding and purple abdominal striae. Her blood pressure is 168/96 mmHg. She is not taking corticosteroids.

 

Test results show:

  • Random glucose: 11.8 mmol/L
  • Potassium: 3.1 mmol/L
  • An overnight low-dose dexamethasone suppression test fails to suppress serum cortisol

What is the SINGLE most appropriate next investigation to determine the cause?

24-hour urinary free cortisol

CT scan of the adrenal glands

High-dose dexamethasone suppression test

MRI scan of the pituitary gland

Plasma ACTH level